ncRNA name | MeCP2 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human umbilical vein endothelial cells (HUVECs) |
Methods | immunohistochemistry, immunofluorescence, siRNA transfection, Western blot |
Expression pattern | associated |
Functional description | We found that phospho-MeCP2-S421 was significantly increased in the membranes from the patients with PDR compared with the specimens from patients without diabetes. Phospho-MeCP2-S421 and VEGF were increased by the stimulation of CoCl2 and knock down MeCP2 inhibited the expression of VEGF. |
PubMed ID | 27616658 |
Year | 2016 |
Title | The significance of the increased expression of phosphorylated MeCP2 in the membranes from patients with proliferative diabetic retinopathy. |
Drug-related ncRNA | NO |
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